Games like Big Pharma on Steam
For those who prefer not to search, lists of the most played, top deals and best free games like Big Pharma are available at the bottom of the page.
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United Penguin Kingdom
A city-building game where you build a penguin settlement and satisfy the various needs of your penguins while dealing with seals and killer whales. Enjoy the growth of your settlement, become the king, and lead the United Penguin Kingdom.
Production Line : Car factory simulation
Production line is the new car factory management/simulation/tycoon game that pushes your organisational and entrepreneurship skills to the limit. Can you build the ultimate optimised, free-flowing car production line whilst beating the competition and still turn a profit?
shapez
shapez is an easy-going, minimalistic factory building game about the automation of shapes through extraction and satisfying production lines. Adapt to increasingly complex shapes and grow your factory across an infinitely expanding map. Your only limitation is your creativity!
Little Big Workshop
Manage your workers, stations, machines and create awesome stuff as your little big workshop grows into your dream factory!
Startup Company
Startup Company is a business simulation sandbox game where you’re the CEO of a new company. Your job is to build your very own website and compete against the largest tech giants on the planet!
RAILGRADE
RAILGRADE is the train RTS game! Construct dense vertical railroads, build cities, construct vast factory chains with train automation! Restore an off world colony's economy all in the intense story driven campaign or relaxing sandbox mode!
Rise of Industry
Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust.
Gunsmith
Build up your own arms manufacturing company. Find your factory, buy resources, produce a wide range of military equipment to sell to the highest bidder. Good or bad? That's up to you, who you do business with is your choice. Don't ask, don't tell, get paid. After all, war is about making money.
OpenTTD
OpenTTD is a business simulation game in which players earn money by transporting passengers and cargo via road, rail, water, and air. It is an open-source remake and expansion of the 1995 Chris Sawyer video game Transport Tycoon Deluxe.
Transport INC
Become the manager of the largest transport corporation ever! Create new planes, bus, trains and truck connections. Optimize them to ever-changing demands and adapt to unexpected events. Beat the competition. Connect cities all around the real world map!
Blueprint Tycoon
Build your settlement, gather goods, ensure maximum efficiency and make a profit!
City Game Studio: Your Game Dev Adventure Begins
Manage a game studio from the dawn of the gaming industry in 1976. Your journey starts with small indie titles and grows into a gaming empire. Develop, design, and conquer the industry. From humble beginnings to gaming legend – it’s your story, your studio, your legacy!
Project Hospital
Become an ace doctor, an aspiring architect and a successful manager at the same time. Design your very own hospital, tweak every detail or choose one of the prebuilt scenarios and just jump to the doctor’s duty.
Megaquarium
The public aquarium simulator. Design your displays, look after your fish, manage your staff and keep your guests happy! It's all in a day's work as the curator of your very own Megaquarium.
Prison Architect
Only the world’s most ruthless Warden can contain the world’s most ruthless inmates. Design and develop your personalized penitentiary in Prison Architect.
Factory Town
Build, automate, and optimize a giant factory on 3D terrain using conveyor belts, trains, chutes, pipes, and airships. Sell your goods to nearby villages to expand their borders, increase happiness, and unlock even better technology!
Hotel Magnate
Have you ever wanted to design and manage your own hotel, rundown motel, or elegant resort? With a ridiculous amount of customization tools to wield, a host of facilities to build, and a wide variety of guests to impress, Hotel Magnate has it all. Let your inner hotel manager shine!
1849
1849 is a city management game set during the California Gold Rush. Your task is to build towns, populate them with workers, and make sure that they are housed, fed, and entertained. You’ll have to manage and coordinate extensive production and trade networks to make sure your towns thrive.
Idle Colony
A condensed incremental experience, where you build a colony to collect and merge bigger and bigger fruits. Combine game-changing technologies and special upgrades to find the best synergies and take your cash flow to another dimension.
Recipe for Disaster
Recipe for Disaster is a management sim that captures the fast-paced, drama-filled environment of a professional kitchen and dining room. Build your dream restaurant, create recipes, design menus and manage your staff, all while contending with demanding customers and disastrous situations!
Potion Tycoon
Potion Tycoon is a management simulator with a witchy twist! Build and develop your very own magic shop. Manage resources, set up production lines, mix potions and sell them smartly to stay ahead of the competition. Welcome to the potion business!
SimAirport
Build & Manage Your Airport. An International Hub or a Regional Masterpiece -- it's up to you. Buy more land to scale out, or escalators to scale up with MULTIPLE FLOORS. You're in full control in this modern business management tycoon!
Laysara: Summit Kingdom
Build and expand your very own settlements in high mountains! Carefully plan production chains and satisfy various needs of your three-caste society while dealing with mountain hazards such as weather breakdowns and avalanches. Are you skilled enough to make your town thrive?
Masterplan Tycoon
Welcome to the resource management game where your creativity and logistics skills are put to the test! In this minimalistic simulation you will build interconnected chains of products and open new missions by completing various tasks to create the biggest system you can.Most played games like Big Pharma on Steam
Take a look at the top games like Big Pharma that are currently attracting the largest player bases on the Steam platform, as of April 15th 2025.
1. RimWorld
Similarity 54% A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more. RimWorld is a colony sim, base-building and survival game developed and published by Ludeon Studios. Released on October 17th 2018 has received 207,285 reviews of which 203,071 were positive and 4,214 were negative resulting in an impressive rating of 9.7 out of 10. The game has hit the top spot as the #1 most played game like Big Pharma, thanks to its 35,684 peak concurrent players over the last day.
9.7
203,071
4,214
35,684
players
2. Factorio
Similarity 66% Factorio is a game about building and creating automated factories to produce items of increasing complexity, within an infinite 2D world. Use your imagination to design your factory, combine simple elements into ingenious structures, and finally protect it from the creatures who don't really like you. Factorio is a automation, base-building and resource management game developed and published by Wube Software LTD.. Released on August 14th 2020 has received 212,622 reviews of which 206,226 were positive and 6,396 were negative resulting in an impressive rating of 9.6 out of 10. While seeing 23,861 players online at once in the last 24 hours, this game is currently ranked #2 among games like Big Pharma based on player count.
9.6
206,226
6,396
23,861
players
3. Cities: Skylines
Similarity 56% Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience. Cities: Skylines is a city builder, simulation and building game developed by Colossal Order Ltd. and published by Paradox Interactive. Released on March 10th 2015 has received 273,442 reviews of which 254,189 were positive and 19,253 were negative resulting in an impressive rating of 9.2 out of 10. While seeing 18,962 players online at once in the last 24 hours, this game is currently ranked #3 among games like Big Pharma based on player count.
9.2
254,189
19,253
18,962
players
4. Cookie Clicker
Similarity 60% An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam. Cookie Clicker is a clicker, idler and casual game developed by Orteil and DashNet and published by Playsaurus. Released on September 01st 2021 has received 78,130 reviews of which 75,535 were positive and 2,595 were negative resulting in an impressive rating of 9.5 out of 10. With 13,767 concurrent players in the last 24 hours, the game currently holds the #4 spot among the most played games like Big Pharma.
9.5
75,535
2,595
13,767
players
5. Oxygen Not Included
Similarity 57% Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive. Oxygen Not Included is a colony sim, base-building and survival game developed and published by Klei Entertainment. Released on July 30th 2019 has received 127,145 reviews of which 123,019 were positive and 4,126 were negative resulting in an impressive rating of 9.5 out of 10. With 13,414 concurrent players in the last 24 hours, the game currently holds the #5 spot among the most played games like Big Pharma.
9.5
123,019
4,126
13,414
players
6. Supermarket Simulator
Similarity 52% Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand and design your store. Online orders & delivery, shoplifters, security, local market are upcoming. Supermarket Simulator is a simulation, management and economy game developed and published by Nokta Games. Released on February 20th 2024 has received 66,396 reviews of which 62,337 were positive and 4,059 were negative resulting in an impressive rating of 9.2 out of 10. With 6,607 concurrent players in the last 24 hours, the game currently holds the #6 spot among the most played games like Big Pharma.
9.2
62,337
4,059
6,607
players
7. Supermarket Together
Similarity 52% The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action! Supermarket Together is a simulation, online co-op and multiplayer game developed and published by DeadDevsTellNoLies. Released on August 09th 2024 has received 62,815 reviews of which 59,688 were positive and 3,127 were negative resulting in an impressive rating of 9.3 out of 10. With 6,579 concurrent players in the last 24 hours, the game currently holds the #7 spot among the most played games like Big Pharma.
9.3
59,688
3,127
6,579
players
8. Dyson Sphere Program
Similarity 65% Build the most efficient intergalactic factory in space simulation strategy game Dyson Sphere Program! Harness the power of stars, collect resources, plan and design production lines and develop your interstellar factory from a small space workshop to a galaxy-wide industrial empire. Dyson Sphere Program is a automation, space and base-building game developed by Youthcat Studio and published by Gamera Games. Released on January 20th 2021 has received 84,564 reviews of which 82,585 were positive and 1,979 were negative resulting in an impressive rating of 9.6 out of 10. With 5,796 concurrent players in the last 24 hours, the game currently holds the #8 spot among the most played games like Big Pharma.
9.6
82,585
1,979
5,796
players
9. Revolution Idle
Similarity 51% Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity? Revolution Idle is a casual, simulation and idler game developed by Oni Gaming and Nu Games and published by Oni Gaming. Released on October 11th 2024 has received 3,526 reviews of which 3,002 were positive and 524 were negative resulting in a rating of 8.2 out of 10. With 5,660 concurrent players in the last 24 hours, the game currently holds the #9 spot among the most played games like Big Pharma.
8.2
3,002
524
5,660
players
10. Planet Zoo
Similarity 54% Build a world for wildlife in Planet Zoo. From the developers of Planet Coaster and Zoo Tycoon comes the ultimate zoo sim. Construct detailed habitats, manage your zoo, and meet authentic living animals who think, feel and explore the world you create around them. Planet Zoo is a management, simulation and building game developed and published by Frontier Developments. Released on November 05th 2019 has received 86,491 reviews of which 78,784 were positive and 7,707 were negative resulting in a rating of 9.0 out of 10. With 5,508 concurrent players in the last 24 hours, the game currently holds the #10 spot among the most played games like Big Pharma.
9.0
78,784
7,707
5,508
players
Best deals on games like Big Pharma on Steam
Discover fantastic savings with the best discounts on a variety of games like Big Pharma available on Steam right now, updated on April 15th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted games like Big Pharma.
1. Naheulbeuk's Dungeon Master
Similarity 51% A dungeon in danger ! Build, manage, and defend your tower in the satirical heroic fantasy universe of Dungeon of Naheulbeuk. From a shaky establishment to an infamous lair! Naheulbeuk's Dungeon Master is a management, simulation and funny game developed by Artefacts Studio and published by Dear Villagers. Released on November 15th 2023 has received 1,373 reviews of which 988 were positive and 385 were negative resulting in a rating of 7.0 out of 10. Featuring a massive 96% discount, this game currently holds the #1 spot in the best deals for games like Big Pharma.
7.0
988
385
-96%
25.00€
1.00€
2. Lords and Villeins
Similarity 59% Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy! Lords and Villeins is a colony sim, strategy and city builder game developed by Honestly Games and published by Fulqrum Publishing. Released on November 10th 2022 has received 865 reviews of which 626 were positive and 239 were negative resulting in a rating of 6.9 out of 10. Thanks to its incredible 96% discount, this game is now the #2 best deal in games like Big Pharma.
6.9
626
239
-96%
27.50€
1.10€
3. Founders' Fortune
Similarity 61% A fantasy village builder focusing on creative building, colonist psychology and base defense. Handle resources, farming, production, tools, diplomacy, families, trading, defense, and research, as well as the wishes, expectations, thoughts, and equipment of every villager. Founders' Fortune is a colony sim, base-building and city builder game developed and published by Dionic Software. Released on December 18th 2020 has received 2,093 reviews of which 1,686 were positive and 407 were negative resulting in a rating of 7.8 out of 10. Thanks to its incredible 95% discount, this game is now the #3 best deal in games like Big Pharma.
7.8
1,686
407
-95%
20.00€
1.00€
4. InfraSpace
Similarity 61% Create an extrasolar efficiency utopia from scratch! In this sci-fi city builder you need to start mining operations, plan production, and lay down transportation routes to ensure a smooth supply chain. InfraSpace is a city builder, automation and transportation game developed and published by Dionic Software. Released on September 22nd 2023 has received 1,611 reviews of which 1,297 were positive and 314 were negative resulting in a rating of 7.7 out of 10. Currently offered at a significant 95% discount, this title has earned the #4 position in the best deals for games like Big Pharma.
7.7
1,297
314
-95%
20.00€
1.00€
5. Autonauts vs Piratebots
Similarity 52% Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones. Autonauts vs Piratebots is a simulation, strategy and automation game developed by Denki and published by Curve Games. Released on July 28th 2022 has received 480 reviews of which 380 were positive and 100 were negative resulting in a rating of 7.5 out of 10. Currently offered at a significant 95% discount, this title has earned the #5 position in the best deals for games like Big Pharma.
7.5
380
100
-95%
20.00€
1.00€
6. Tin Can
Similarity 51% You've barely managed to escape your exploding spaceship. Now in an old escape pod, you hurtle through space at the mercy of the cosmos. With no knowledge of the pod’s complex systems, your life depends on a technical manual and your own wits. How long can you survive? Tin Can is a simulation, space and survival game developed by Tin Can Studio and published by Tin Can Studio and IndieArk. Released on May 12th 2022 has received 1,167 reviews of which 990 were positive and 177 were negative resulting in a rating of 8.1 out of 10. Currently offered at a significant 94% discount, this title has earned the #6 position in the best deals for games like Big Pharma.
8.1
990
177
-94%
16.67€
1.00€
7. Snowtopia: Ski Resort Builder
Similarity 60% Build your ideal ski resort. Keep skiers smiling with fresh pistes and fine facilities. Ski, build and chill in the wintry world of Snowtopia where everyone is welcome! Snowtopia: Ski Resort Builder is a simulation, building and management game developed by TeaForTwo and published by Goblinz Publishing and Maple Whispering Limited. Released on December 14th 2022 has received 1,162 reviews of which 713 were positive and 449 were negative resulting in a rating of 6 out of 10. Currently offered at a significant 94% discount, this title has earned the #7 position in the best deals for games like Big Pharma.
6
713
449
-94%
19.83€
1.19€
8. Life is Feudal: Forest Village
Similarity 53% LiF:Forest Village is a city builder with survival aspects in a realistic harsh medieval world. Shape, build and expand your settlement, grow various food to prevent your villagers from avitaminosis and starvation. Possess them for additional micromanagement or simply to wander around. Life is Feudal: Forest Village is a city builder, colony sim and strategy game developed by Mindillusion and published by Bitbox Ltd.. Released on May 26th 2017 has received 5,873 reviews of which 3,892 were positive and 1,981 were negative resulting in a rating of 6.5 out of 10. Currently offered at a significant 93% discount, this title has earned the #8 position in the best deals for games like Big Pharma.
6.5
3,892
1,981
-93%
24.57€
1.72€
9. Train Valley 2
Similarity 54% Build bigger and more complex railway networks than ever before! Building on the success of the original, you’ll get more of what you loved about the original and then some. With increasingly difficult and complex challenges from local industries, the Valley has never felt so vast! ALL ABOARD! Train Valley 2 is a multiple endings, quick-time events and trains game developed by Alexey Davydov, Sergey Dvoynikov, Timofey Shargorodskiy and Flazm and published by Flazm and META Publishing. Released on April 15th 2019 has received 2,847 reviews of which 2,570 were positive and 277 were negative resulting in a rating of 8.7 out of 10. Currently offered at a significant 92% discount, this title has earned the #9 position in the best deals for games like Big Pharma.
8.7
2,570
277
-92%
12.50€
1.00€
10. Rise of Industry
Similarity 72% Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust. Rise of Industry is a management, strategy and economy game developed by Dapper Penguin Studios and published by Kasedo Games. Released on May 02nd 2019 has received 4,084 reviews of which 2,993 were positive and 1,091 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 92% discount, this title has earned the #10 position in the best deals for games like Big Pharma.
7.1
2,993
1,091
-92%
30.63€
2.45€
Free games like Big Pharma on Steam
Check out this fantastic list of free-to-play games like Big Pharma you can enjoy on Steam right now, updated on April 15th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play games like Big Pharma.
1. Supermarket Together
Similarity 52% The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action! Supermarket Together is a simulation, online co-op and multiplayer game developed and published by DeadDevsTellNoLies. Released on August 09th 2024 has received 62,815 reviews of which 59,688 were positive and 3,127 were negative resulting in an impressive rating of 9.3 out of 10. With 6,579 active players enjoying it for free, this strategy game has reached the #1 spot among the top free games like Big Pharma.
9.3
59,688
3,127
6,579
players
2. Revolution Idle
Similarity 51% Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity? Revolution Idle is a casual, simulation and idler game developed by Oni Gaming and Nu Games and published by Oni Gaming. Released on October 11th 2024 has received 3,526 reviews of which 3,002 were positive and 524 were negative resulting in a rating of 8.2 out of 10. Thanks to its free to play tag and a daily player base of 5,660, this game has secured the #2 spot in the ranking of free games like Big Pharma.
8.2
3,002
524
5,660
players
3. Mr.Mine
Similarity 54% Explore the depths of the earth and uncover hidden treasures in this addictive idle mining game. Unlock the power of your drill with hundreds of upgrades, discover mysterious relics, and unearth priceless gems. Can you master the mines and reveal their deepest secrets? Dive in and dig deep! Mr.Mine is a idler, clicker and strategy game developed and published by Playsaurus. Released on September 30th 2020 has received 16,877 reviews of which 15,520 were positive and 1,357 were negative resulting in a rating of 9.0 out of 10. Thanks to its free to play tag and a daily player base of 1,260, this game has secured the #3 spot in the ranking of free games like Big Pharma.
9.0
15,520
1,357
1,260
players
4. OpenTTD
Similarity 71% OpenTTD is a business simulation game in which players earn money by transporting passengers and cargo via road, rail, water, and air. It is an open-source remake and expansion of the 1995 Chris Sawyer video game Transport Tycoon Deluxe. OpenTTD is a simulation, building and free to play game developed and published by OpenTTD. Released on April 01st 2021 has received 14,119 reviews of which 13,577 were positive and 542 were negative resulting in an impressive rating of 9.4 out of 10. Attracting a solid base of 749 players due to its free access, this strategy game has achieved the #4 position in the best free games like Big Pharma.
9.4
13,577
542
749
players
5. Idle Spiral
Similarity 53% This is a beautiful "Idle", "Incremental" game based on spirals and mathematics. Your goal is to make the spiral grow farther and farther from the origin. The game is very simple, but it is very deep and can be enjoyed for a long time! Idle Spiral is a idler, simulation and clicker game developed by Idle System, Inc. and Yayu and published by Idle System and Inc.. Released on April 30th 2022 has received 1,743 reviews of which 1,416 were positive and 327 were negative resulting in a rating of 7.8 out of 10. Attracting a solid base of 257 players due to its free access, this strategy game has achieved the #5 position in the best free games like Big Pharma.
7.8
1,416
327
257
players
6. CivIdle
Similarity 54% CivIdle is an idle/incremental game that allows you to lead your own civilization through thousands of years from ancient times to the modern era. Expand your territory, explore a vast tech tree, build various wonders, and trade with global players: empire must grow and numbers must go up! CivIdle is a early access, idler and base building game developed and published by Fish Pond Studio. Released on February 16th 2024 has received 606 reviews of which 457 were positive and 149 were negative resulting in a rating of 7.2 out of 10. Attracting a solid base of 211 players due to its free access, this strategy game has achieved the #6 position in the best free games like Big Pharma.
7.2
457
149
211
players
7. Global City
Similarity 56% Become the mayor and build the city of your dreams! In this game, anything is possible. Whatever you can imagine in a city-building and development simulator, you can do. Start from the very beginning and unlock new possibilities for developing your city in Global City! Global City is a city builder, strategy and building game developed by Red Brix Wall and published by MY.GAMES. Released on November 30th 2021 has received 1,157 reviews of which 813 were positive and 344 were negative resulting in a rating of 6.8 out of 10. Attracting a solid base of 179 players due to its free access, this strategy game has achieved the #7 position in the best free games like Big Pharma.
6.8
813
344
179
players
8. Sim Companies
Similarity 51% Become a Business Tycoon. Build your own company from the ground up. Do business in a virtual economy with players all around the world! Gain valuable business skills for free. An advanced, proprietary, Economy simulation model is used to deliver the best gaming experience. Sim Companies is a economy, capitalism and simulation game developed and published by Sim Companies s.r.o.. Released on August 31st 2023 has received 827 reviews of which 663 were positive and 164 were negative resulting in a rating of 7.6 out of 10. Attracting a solid base of 146 players due to its free access, this strategy game has achieved the #8 position in the best free games like Big Pharma.
7.6
663
164
146
players
9. Learn to Fly 3
Similarity 59% Build your spaceship from scratch, earn funds and invest them into building a bigger, better spaceship as you try and fly your way up to space! Learn to Fly 3 is a free to play, casual and simulation game developed and published by Light Bringer Games inc.. Released on May 12th 2017 has received 10,251 reviews of which 9,696 were positive and 555 were negative resulting in an impressive rating of 9.2 out of 10. The game currently holds the #9 spot among the most played free games like Big Pharma.
9.2
9,696
555
92
players
10. Sarah's Adventure: Time Travel
Similarity 53% This game unearths the essence of adventure by combining elements of exploration and puzzle-solving. The game’s appeal lies in its interactive gameplay mechanics, where your choices dictate the progression of the story. Sarah's Adventure: Time Travel is a casual, simulation and free to play game developed and published by NUTS POWER ONLINE ENTERTAINMENT LIMITED. Released on June 25th 2024 has received 2,003 reviews of which 1,820 were positive and 183 were negative resulting in a rating of 8.7 out of 10. The game currently holds the #10 spot among the most played free games like Big Pharma.
8.7
1,820
183
80
players