Games like Big Pharma on Steam
For those who prefer not to search, lists of the most played, top deals and best free games like Big Pharma are available at the bottom of the page.
Internet Cafe Evolution
This is a business simulation + construction game. It tells the evolution history of Internet cafes that began in the 1990s, and imagines the future of internet cafes. There are also some small emotional stories.Word Factori
Word Factori is a word-building game where your only resource is the letter "i". Build a chain of factories to bend, rotate, reflect, and merge "i" into more complex letters. Discover secret letter recipes, unlock hidden word art, and optimize your factory chains for high scores.The Sushi Spinnery
Revolutionize the revolving sushi bar in this fresh new sim!Craftomation 101: Programming & Craft
You land on a frozen planet in a tiny rocket with a robot inside. Harvest and combine materials to discover new ones. Use visual programming to make the robot do the tiresome work for you. Slowly build a gang of self-sustaining robot workers and watch them terraform the planet.Urbek City Builder
Urbek is a city building game where you can build your own neighbourhoods: from nightlife district to industrial district. Don't exhaust your natural resources before you have an educated population to build more efficient structures.Rec Center Tycoon - Management Simulator
Design, build and manage a recreation center! Host fitness classes, build swimming pools, arcade & entertainment areas, build event rooms to host parties & much more. With endless customisation, Rec Center Tycoon goes much more in-depth than your average business management simulator.Weedcraft Inc
Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant.Project AURA
Project Aura is a micro management game where you lead a Colony of Climate Disaster Survivors. You have been assigned the mission to build an habitat capable of survival in this new unknown world.Reus 2
Shape worlds with your godly titans. Make symbiotic ecosystems and inspire humanity with your creations. Their achievements unlock new possibilities. Make different planets for different human spirits, and fill the universe with life!Reus
In Reus, you control powerful giants to shape the planet to your will. You can create mountains, oceans, forests and more. Enrich your planet with plants, minerals and animal life. There is only one thing on the planet that you do not control: mankind, with all their virtues and and all their vices.Sweet Transit
Sweet Transit is a unique city builder where the railway is king. Build and automate the dream supply chain for your citizens, giving them all they need to expand quaint villages into bustling cities. Progress from steam power to diesel and beyond in this advanced train-driven experience.Hell Architect
Hell Architect is a game about building and managing your own hell. You take on a role of a hell manager and are tasked with developing the underworld in a way that would make Lucifer himself fall off his chair.First Feudal
Become a real medieval feudal lord: start with a small village and build it up into an enormous impenetrable castle. You will have to repel enemy raids: hide behind thick walls, lure your enemies into strategically placed traps, and even lead your loyal peasants into battle.MachiaVillain
Machiavillain is an evil mansion management and strategy game, inspired by Dungeon Keeper, Prison Architect and all the horror movie clichés! Build your own manor, raise your monsters, set up your traps, and exterminate your victims. But to gain reputation you'll have to slay by the horror movie rules!Judgment: Apocalypse Survival Simulation
Build, scavenge, craft, and perform occult rituals to survive in a demon-infested, post-apocalyptic colony simulation. Will you survive Judgment day?Basement
Basement is a strategy game, where you start doing illegal business to fund the development of your dream video game. It won't be easy, so get ready to deal with other gangs, cops, crazy junkies, mysterious investor and even ghosts from the past.Two Point Campus
Build the university of your dreams with Two Point Campus, the sim with a twist from the makers of Two Point Hospital. Build, hire staff and run an academic institution packed with wild courses.Transport Fever 2
The classic transport simulation genre has a new gold standard with Transport Fever 2. Discover a whole new world by navigating transport routes through land, water and air. May progress and prosperity find their way!Project Highrise
Project Highrise is a skyscraper construction and management sim...Kubifaktorium
Build, manage and grow a thriving colony in Kubifaktorium. The game features different biomes to explore, plenty of resources to exploit, complex machinery to build and interesting production chains to master.Galacticare
Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.Sixty Four
Dive into the world of Sixty Four, where you transform simple machines into a thriving factory.InfraSpace
Create an extrasolar efficiency utopia from scratch! In this sci-fi city builder you need to start mining operations, plan production, and lay down transportation routes to ensure a smooth supply chain.Most played games like Big Pharma on Steam
Take a look at the top games like Big Pharma that are currently attracting the largest player bases on the Steam platform, as of April 15th 2025.
1. RimWorld
Similarity 54% A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more. RimWorld is a colony sim, base-building and survival game developed and published by Ludeon Studios. Released on October 17th 2018 has received 207,285 reviews of which 203,071 were positive and 4,214 were negative resulting in an impressive rating of 9.7 out of 10. The game has hit the top spot as the #1 most played game like Big Pharma, thanks to its 35,684 peak concurrent players over the last day.2. Factorio
Similarity 66% Factorio is a game about building and creating automated factories to produce items of increasing complexity, within an infinite 2D world. Use your imagination to design your factory, combine simple elements into ingenious structures, and finally protect it from the creatures who don't really like you. Factorio is a automation, base-building and resource management game developed and published by Wube Software LTD.. Released on August 14th 2020 has received 212,622 reviews of which 206,226 were positive and 6,396 were negative resulting in an impressive rating of 9.6 out of 10. While seeing 23,861 players online at once in the last 24 hours, this game is currently ranked #2 among games like Big Pharma based on player count.3. Cities: Skylines
Similarity 56% Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience. Cities: Skylines is a city builder, simulation and building game developed by Colossal Order Ltd. and published by Paradox Interactive. Released on March 10th 2015 has received 273,442 reviews of which 254,189 were positive and 19,253 were negative resulting in an impressive rating of 9.2 out of 10. While seeing 18,962 players online at once in the last 24 hours, this game is currently ranked #3 among games like Big Pharma based on player count.4. Cookie Clicker
Similarity 60% An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam. Cookie Clicker is a clicker, idler and casual game developed by Orteil and DashNet and published by Playsaurus. Released on September 01st 2021 has received 78,130 reviews of which 75,535 were positive and 2,595 were negative resulting in an impressive rating of 9.5 out of 10. With 13,767 concurrent players in the last 24 hours, the game currently holds the #4 spot among the most played games like Big Pharma.5. Oxygen Not Included
Similarity 57% Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive. Oxygen Not Included is a colony sim, base-building and survival game developed and published by Klei Entertainment. Released on July 30th 2019 has received 127,145 reviews of which 123,019 were positive and 4,126 were negative resulting in an impressive rating of 9.5 out of 10. With 13,414 concurrent players in the last 24 hours, the game currently holds the #5 spot among the most played games like Big Pharma.6. Supermarket Simulator
Similarity 52% Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand and design your store. Online orders & delivery, shoplifters, security, local market are upcoming. Supermarket Simulator is a simulation, management and economy game developed and published by Nokta Games. Released on February 20th 2024 has received 66,396 reviews of which 62,337 were positive and 4,059 were negative resulting in an impressive rating of 9.2 out of 10. With 6,607 concurrent players in the last 24 hours, the game currently holds the #6 spot among the most played games like Big Pharma.7. Supermarket Together
Similarity 52% The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action! Supermarket Together is a simulation, online co-op and multiplayer game developed and published by DeadDevsTellNoLies. Released on August 09th 2024 has received 62,815 reviews of which 59,688 were positive and 3,127 were negative resulting in an impressive rating of 9.3 out of 10. With 6,579 concurrent players in the last 24 hours, the game currently holds the #7 spot among the most played games like Big Pharma.8. Dyson Sphere Program
Similarity 65% Build the most efficient intergalactic factory in space simulation strategy game Dyson Sphere Program! Harness the power of stars, collect resources, plan and design production lines and develop your interstellar factory from a small space workshop to a galaxy-wide industrial empire. Dyson Sphere Program is a automation, space and base-building game developed by Youthcat Studio and published by Gamera Games. Released on January 20th 2021 has received 84,564 reviews of which 82,585 were positive and 1,979 were negative resulting in an impressive rating of 9.6 out of 10. With 5,796 concurrent players in the last 24 hours, the game currently holds the #8 spot among the most played games like Big Pharma.9. Revolution Idle
Similarity 51% Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity? Revolution Idle is a casual, simulation and idler game developed by Oni Gaming and Nu Games and published by Oni Gaming. Released on October 11th 2024 has received 3,526 reviews of which 3,002 were positive and 524 were negative resulting in a rating of 8.2 out of 10. With 5,660 concurrent players in the last 24 hours, the game currently holds the #9 spot among the most played games like Big Pharma.10. Planet Zoo
Similarity 54% Build a world for wildlife in Planet Zoo. From the developers of Planet Coaster and Zoo Tycoon comes the ultimate zoo sim. Construct detailed habitats, manage your zoo, and meet authentic living animals who think, feel and explore the world you create around them. Planet Zoo is a management, simulation and building game developed and published by Frontier Developments. Released on November 05th 2019 has received 86,491 reviews of which 78,784 were positive and 7,707 were negative resulting in a rating of 9.0 out of 10. With 5,508 concurrent players in the last 24 hours, the game currently holds the #10 spot among the most played games like Big Pharma.Best deals on games like Big Pharma on Steam
Discover fantastic savings with the best discounts on a variety of games like Big Pharma available on Steam right now, updated on April 15th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted games like Big Pharma.
1. Naheulbeuk's Dungeon Master
Similarity 51% A dungeon in danger ! Build, manage, and defend your tower in the satirical heroic fantasy universe of Dungeon of Naheulbeuk. From a shaky establishment to an infamous lair! Naheulbeuk's Dungeon Master is a management, simulation and funny game developed by Artefacts Studio and published by Dear Villagers. Released on November 15th 2023 has received 1,373 reviews of which 988 were positive and 385 were negative resulting in a rating of 7.0 out of 10. Featuring a massive 96% discount, this game currently holds the #1 spot in the best deals for games like Big Pharma.2. Lords and Villeins
Similarity 59% Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy! Lords and Villeins is a colony sim, strategy and city builder game developed by Honestly Games and published by Fulqrum Publishing. Released on November 10th 2022 has received 865 reviews of which 626 were positive and 239 were negative resulting in a rating of 6.9 out of 10. Thanks to its incredible 96% discount, this game is now the #2 best deal in games like Big Pharma.3. Founders' Fortune
Similarity 61% A fantasy village builder focusing on creative building, colonist psychology and base defense. Handle resources, farming, production, tools, diplomacy, families, trading, defense, and research, as well as the wishes, expectations, thoughts, and equipment of every villager. Founders' Fortune is a colony sim, base-building and city builder game developed and published by Dionic Software. Released on December 18th 2020 has received 2,093 reviews of which 1,686 were positive and 407 were negative resulting in a rating of 7.8 out of 10. Thanks to its incredible 95% discount, this game is now the #3 best deal in games like Big Pharma.4. InfraSpace
Similarity 61% Create an extrasolar efficiency utopia from scratch! In this sci-fi city builder you need to start mining operations, plan production, and lay down transportation routes to ensure a smooth supply chain. InfraSpace is a city builder, automation and transportation game developed and published by Dionic Software. Released on September 22nd 2023 has received 1,611 reviews of which 1,297 were positive and 314 were negative resulting in a rating of 7.7 out of 10. Currently offered at a significant 95% discount, this title has earned the #4 position in the best deals for games like Big Pharma.5. Autonauts vs Piratebots
Similarity 52% Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones. Autonauts vs Piratebots is a simulation, strategy and automation game developed by Denki and published by Curve Games. Released on July 28th 2022 has received 480 reviews of which 380 were positive and 100 were negative resulting in a rating of 7.5 out of 10. Currently offered at a significant 95% discount, this title has earned the #5 position in the best deals for games like Big Pharma.6. Tin Can
Similarity 51% You've barely managed to escape your exploding spaceship. Now in an old escape pod, you hurtle through space at the mercy of the cosmos. With no knowledge of the pod’s complex systems, your life depends on a technical manual and your own wits. How long can you survive? Tin Can is a simulation, space and survival game developed by Tin Can Studio and published by Tin Can Studio and IndieArk. Released on May 12th 2022 has received 1,167 reviews of which 990 were positive and 177 were negative resulting in a rating of 8.1 out of 10. Currently offered at a significant 94% discount, this title has earned the #6 position in the best deals for games like Big Pharma.7. Snowtopia: Ski Resort Builder
Similarity 60% Build your ideal ski resort. Keep skiers smiling with fresh pistes and fine facilities. Ski, build and chill in the wintry world of Snowtopia where everyone is welcome! Snowtopia: Ski Resort Builder is a simulation, building and management game developed by TeaForTwo and published by Goblinz Publishing and Maple Whispering Limited. Released on December 14th 2022 has received 1,162 reviews of which 713 were positive and 449 were negative resulting in a rating of 6 out of 10. Currently offered at a significant 94% discount, this title has earned the #7 position in the best deals for games like Big Pharma.8. Life is Feudal: Forest Village
Similarity 53% LiF:Forest Village is a city builder with survival aspects in a realistic harsh medieval world. Shape, build and expand your settlement, grow various food to prevent your villagers from avitaminosis and starvation. Possess them for additional micromanagement or simply to wander around. Life is Feudal: Forest Village is a city builder, colony sim and strategy game developed by Mindillusion and published by Bitbox Ltd.. Released on May 26th 2017 has received 5,873 reviews of which 3,892 were positive and 1,981 were negative resulting in a rating of 6.5 out of 10. Currently offered at a significant 93% discount, this title has earned the #8 position in the best deals for games like Big Pharma.9. Train Valley 2
Similarity 54% Build bigger and more complex railway networks than ever before! Building on the success of the original, you’ll get more of what you loved about the original and then some. With increasingly difficult and complex challenges from local industries, the Valley has never felt so vast! ALL ABOARD! Train Valley 2 is a multiple endings, quick-time events and trains game developed by Alexey Davydov, Sergey Dvoynikov, Timofey Shargorodskiy and Flazm and published by Flazm and META Publishing. Released on April 15th 2019 has received 2,847 reviews of which 2,570 were positive and 277 were negative resulting in a rating of 8.7 out of 10. Currently offered at a significant 92% discount, this title has earned the #9 position in the best deals for games like Big Pharma.10. Rise of Industry
Similarity 72% Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust. Rise of Industry is a management, strategy and economy game developed by Dapper Penguin Studios and published by Kasedo Games. Released on May 02nd 2019 has received 4,084 reviews of which 2,993 were positive and 1,091 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 92% discount, this title has earned the #10 position in the best deals for games like Big Pharma.Free games like Big Pharma on Steam
Check out this fantastic list of free-to-play games like Big Pharma you can enjoy on Steam right now, updated on April 15th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play games like Big Pharma.