Games like Big Pharma on Steam
For those who prefer not to search, lists of the most played, top deals and best free games like Big Pharma are available at the bottom of the page.
Prehistoric Kingdom
Take control of limitless power in Prehistoric Kingdom to build, manage and grow the ultimate zoo for extinct animals.Banished
In this city-building strategy game, you control a group of exiled travelers who decide to restart their lives in a new land. They have only the clothes on their backs and a cart filled with supplies from their homeland. The townspeople of Banished are your primary resource.Microtopia
Become the hive mind of a robot ant colony in Microtopia! Use pheromone trails to create, automate and optimize supply chains for your ants to follow. Collect resources, produce goods, feed your queen, grow your colony and fly out to expand the species!Gold Mining Simulator
Become a gold miner. Work hard, dig deep, explore the world, and you’ll become the wealthiest person in Alaska. Use a variety of specialist machines to find as much gold as you can.Two Point Museum
Curate and manage incredible museums! Explore to discover amazing artifacts. Design and refine the layout, keep staff happy, guests entertained, donations plentiful… and children off the exhibitsAnvil Saga
Anvil Saga is a management sim with RPG elements where you take control of a blacksmith shop amidst the Hundred Years' War. Each decision you make impacts the story and gameplay.Spellcaster University
Develop a prestigious university of mages. Build rooms, train your students, fight orcs, slay the bureaucrats, manage your budget... a director's life is not a quiet one.House Flipper
House Flipper is a unique chance to become a one-man renovation crew. Buy, repair and remodel devastated houses. Give them a second life and sell them at a profit!Norland
Lead your noble family in this medieval colony sim, facing off against class conflict, religious struggle, and political treachery. Tend to your people’s needs, uncover the lost knowledge of a fallen empire, and engage in nefarious plots against your enemies.Patron
Patron is a survival city builder with a unique social dynamics system. Gather and produce resources, build your fledgling village into a prosperous city and navigate the intricate social tensions before they reach boiling point.Cataclismo
Design and build fortresses brick by brick to stand against endless hordes of Horrors in this real-time strategy game with resource management, siege defense, and exploration. Lead from the ramparts, push back the darkness, and hold fast against the creatures of the Mist.Manor Lords
Manor Lords is a medieval strategy game featuring in-depth city building, large-scale tactical battles, and complex economic and social simulations. Rule your lands as a medieval lord – the seasons pass, the weather changes, and cities rise and fall.Airborne Kingdom
The sky city builder awaits. Create your own flying kingdom and lead it on a quest across an expansive world. Explore the varied landscape, build up a floating metropolis, aid struggling people below, uncover lost secrets and, ultimately, bring back the Airborne Kingdom legend.Workers & Resources: Soviet Republic
Build a soviet republic from an impoverished country into a rich industrial superpower in a city builder with intricate production chains and a fully simulated global economy. Manage the lives of your citizens from education to work and party loyalty to criminal activity.Planet Zoo
Build a world for wildlife in Planet Zoo. From the developers of Planet Coaster and Zoo Tycoon comes the ultimate zoo sim. Construct detailed habitats, manage your zoo, and meet authentic living animals who think, feel and explore the world you create around them.Train Valley 2
Build bigger and more complex railway networks than ever before! Building on the success of the original, you’ll get more of what you loved about the original and then some. With increasingly difficult and complex challenges from local industries, the Valley has never felt so vast! ALL ABOARD!Terroir
Terroir is a 3D tile-based tycoon game where you manage your very own vineyard. In Terroir, you grow a variety of different grape varietals, craft your wine, and expand and manage your Chateau, all the while dealing with the weather and events that can either make or break your business.Empires of the Undergrowth
Command swarms of warriors at an unprecedented scale of warfare in this blend of RTS and base-building. Lead ant colonies against the many fearsome threats of the insect world, while building intricate nests, developing pheromone-based tactics, and evolving to meet growing dangers.RimWorld
A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.Park Beyond
Park Beyond is a theme park simulation game that gives you the freedom to create and manage the Parks of your Dreams! Whether you love to manage finances and visitor experience, or just create fun and cozy parks, the game has something in store just for you!Mars Power Industries Deluxe
Mysterious puzzle inspired by 2001:Space Odyssey. Manage resources, solve challenging puzzles and uncover what lies beneath the surface! Year after year, strange happenings plague our tiny colony, darkness devours Mars. Your job as an Electrician? Bring light where darkness reigns!Dawn of Man
Command a settlement of ancient humans, guide them through the ages in their struggle for survival. Hunt, gather, craft tools, fight, research new techs and face the challenges the environment will throw at you.112 Operator
Manage emergency services in any city in the world! Take calls and dispatch rescue forces. Handle difficult situations, now depending on the weather, and traffic. Help the citizens through cataclysms and natural disasters, becoming a better emergency number operator every day!Most played games like Big Pharma on Steam
Take a look at the top games like Big Pharma that are currently attracting the largest player bases on the Steam platform, as of April 19th 2025.
1. RimWorld
Similarity 54% A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more. RimWorld is a colony sim, base-building and survival game developed and published by Ludeon Studios. Released on October 17th 2018 has received 207,748 reviews of which 203,531 were positive and 4,217 were negative resulting in an impressive rating of 9.7 out of 10. The game has hit the top spot as the #1 most played game like Big Pharma, thanks to its 22,530 peak concurrent players over the last day.2. Factorio
Similarity 66% Factorio is a game about building and creating automated factories to produce items of increasing complexity, within an infinite 2D world. Use your imagination to design your factory, combine simple elements into ingenious structures, and finally protect it from the creatures who don't really like you. Factorio is a automation, base-building and resource management game developed and published by Wube Software LTD.. Released on August 14th 2020 has received 212,622 reviews of which 206,226 were positive and 6,396 were negative resulting in an impressive rating of 9.6 out of 10. While seeing 18,327 players online at once in the last 24 hours, this game is currently ranked #2 among games like Big Pharma based on player count.3. Cookie Clicker
Similarity 60% An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam. Cookie Clicker is a clicker, idler and casual game developed by Orteil and DashNet and published by Playsaurus. Released on September 01st 2021 has received 78,398 reviews of which 75,801 were positive and 2,597 were negative resulting in an impressive rating of 9.5 out of 10. While seeing 12,055 players online at once in the last 24 hours, this game is currently ranked #3 among games like Big Pharma based on player count.4. Revolution Idle
Similarity 51% Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity? Revolution Idle is a casual, simulation and idler game developed by Oni Gaming and Nu Games and published by Oni Gaming. Released on October 11th 2024 has received 3,526 reviews of which 3,002 were positive and 524 were negative resulting in a rating of 8.2 out of 10. With 7,579 concurrent players in the last 24 hours, the game currently holds the #4 spot among the most played games like Big Pharma.5. Cities: Skylines
Similarity 56% Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience. Cities: Skylines is a city builder, simulation and building game developed by Colossal Order Ltd. and published by Paradox Interactive. Released on March 10th 2015 has received 273,857 reviews of which 254,575 were positive and 19,282 were negative resulting in an impressive rating of 9.2 out of 10. With 7,553 concurrent players in the last 24 hours, the game currently holds the #5 spot among the most played games like Big Pharma.6. Supermarket Together
Similarity 52% The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action! Supermarket Together is a simulation, online co-op and multiplayer game developed and published by DeadDevsTellNoLies. Released on August 09th 2024 has received 63,629 reviews of which 60,450 were positive and 3,179 were negative resulting in an impressive rating of 9.3 out of 10. With 6,666 concurrent players in the last 24 hours, the game currently holds the #6 spot among the most played games like Big Pharma.7. Oxygen Not Included
Similarity 57% Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive. Oxygen Not Included is a colony sim, base-building and survival game developed and published by Klei Entertainment. Released on July 30th 2019 has received 127,145 reviews of which 123,019 were positive and 4,126 were negative resulting in an impressive rating of 9.5 out of 10. With 5,652 concurrent players in the last 24 hours, the game currently holds the #7 spot among the most played games like Big Pharma.8. Planet Zoo
Similarity 54% Build a world for wildlife in Planet Zoo. From the developers of Planet Coaster and Zoo Tycoon comes the ultimate zoo sim. Construct detailed habitats, manage your zoo, and meet authentic living animals who think, feel and explore the world you create around them. Planet Zoo is a management, simulation and building game developed and published by Frontier Developments. Released on November 05th 2019 has received 86,491 reviews of which 78,784 were positive and 7,707 were negative resulting in a rating of 9.0 out of 10. With 4,094 concurrent players in the last 24 hours, the game currently holds the #8 spot among the most played games like Big Pharma.9. Supermarket Simulator
Similarity 52% Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand and design your store. Online orders & delivery, shoplifters, security, local market are upcoming. Supermarket Simulator is a simulation, management and economy game developed and published by Nokta Games. Released on February 20th 2024 has received 66,396 reviews of which 62,337 were positive and 4,059 were negative resulting in an impressive rating of 9.2 out of 10. With 4,043 concurrent players in the last 24 hours, the game currently holds the #9 spot among the most played games like Big Pharma.10. Manor Lords
Similarity 54% Manor Lords is a medieval strategy game featuring in-depth city building, large-scale tactical battles, and complex economic and social simulations. Rule your lands as a medieval lord – the seasons pass, the weather changes, and cities rise and fall. Manor Lords is a strategy, city builder and simulation game developed by Slavic Magic and published by Hooded Horse. Released on April 26th 2024 has received 70,570 reviews of which 61,069 were positive and 9,501 were negative resulting in a rating of 8.5 out of 10. With 2,899 concurrent players in the last 24 hours, the game currently holds the #10 spot among the most played games like Big Pharma.Best deals on games like Big Pharma on Steam
Discover fantastic savings with the best discounts on a variety of games like Big Pharma available on Steam right now, updated on April 19th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted games like Big Pharma.
1. Naheulbeuk's Dungeon Master
Similarity 51% A dungeon in danger ! Build, manage, and defend your tower in the satirical heroic fantasy universe of Dungeon of Naheulbeuk. From a shaky establishment to an infamous lair! Naheulbeuk's Dungeon Master is a management, simulation and funny game developed by Artefacts Studio and published by Dear Villagers. Released on November 15th 2023 has received 1,373 reviews of which 988 were positive and 385 were negative resulting in a rating of 7.0 out of 10. Featuring a massive 96% discount, this game currently holds the #1 spot in the best deals for games like Big Pharma.2. Lords and Villeins
Similarity 59% Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy! Lords and Villeins is a colony sim, strategy and city builder game developed by Honestly Games and published by Fulqrum Publishing. Released on November 10th 2022 has received 868 reviews of which 628 were positive and 240 were negative resulting in a rating of 6.9 out of 10. Thanks to its incredible 96% discount, this game is now the #2 best deal in games like Big Pharma.3. Founders' Fortune
Similarity 61% A fantasy village builder focusing on creative building, colonist psychology and base defense. Handle resources, farming, production, tools, diplomacy, families, trading, defense, and research, as well as the wishes, expectations, thoughts, and equipment of every villager. Founders' Fortune is a colony sim, base-building and city builder game developed and published by Dionic Software. Released on December 18th 2020 has received 2,097 reviews of which 1,688 were positive and 409 were negative resulting in a rating of 7.7 out of 10. Thanks to its incredible 95% discount, this game is now the #3 best deal in games like Big Pharma.4. InfraSpace
Similarity 61% Create an extrasolar efficiency utopia from scratch! In this sci-fi city builder you need to start mining operations, plan production, and lay down transportation routes to ensure a smooth supply chain. InfraSpace is a city builder, automation and transportation game developed and published by Dionic Software. Released on September 22nd 2023 has received 1,611 reviews of which 1,297 were positive and 314 were negative resulting in a rating of 7.7 out of 10. Currently offered at a significant 95% discount, this title has earned the #4 position in the best deals for games like Big Pharma.5. Autonauts vs Piratebots
Similarity 52% Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones. Autonauts vs Piratebots is a simulation, strategy and automation game developed by Denki and published by Curve Games. Released on July 28th 2022 has received 480 reviews of which 380 were positive and 100 were negative resulting in a rating of 7.5 out of 10. Currently offered at a significant 95% discount, this title has earned the #5 position in the best deals for games like Big Pharma.6. Tin Can
Similarity 51% You've barely managed to escape your exploding spaceship. Now in an old escape pod, you hurtle through space at the mercy of the cosmos. With no knowledge of the pod’s complex systems, your life depends on a technical manual and your own wits. How long can you survive? Tin Can is a simulation, space and survival game developed by Tin Can Studio and published by Tin Can Studio and IndieArk. Released on May 12th 2022 has received 1,175 reviews of which 995 were positive and 180 were negative resulting in a rating of 8.1 out of 10. Currently offered at a significant 94% discount, this title has earned the #6 position in the best deals for games like Big Pharma.7. Snowtopia: Ski Resort Builder
Similarity 60% Build your ideal ski resort. Keep skiers smiling with fresh pistes and fine facilities. Ski, build and chill in the wintry world of Snowtopia where everyone is welcome! Snowtopia: Ski Resort Builder is a simulation, building and management game developed by TeaForTwo and published by Goblinz Publishing and Maple Whispering Limited. Released on December 14th 2022 has received 1,165 reviews of which 714 were positive and 451 were negative resulting in a rating of 6.0 out of 10. Currently offered at a significant 94% discount, this title has earned the #7 position in the best deals for games like Big Pharma.8. 112 Operator
Similarity 54% Manage emergency services in any city in the world! Take calls and dispatch rescue forces. Handle difficult situations, now depending on the weather, and traffic. Help the citizens through cataclysms and natural disasters, becoming a better emergency number operator every day! 112 Operator is a simulation, realistic and casual game developed by Jutsu Games and published by Games Operators. Released on April 23rd 2020 has received 6,469 reviews of which 5,790 were positive and 679 were negative resulting in a rating of 8.7 out of 10. Currently offered at a significant 92% discount, this title has earned the #8 position in the best deals for games like Big Pharma.9. Train Valley 2
Similarity 54% Build bigger and more complex railway networks than ever before! Building on the success of the original, you’ll get more of what you loved about the original and then some. With increasingly difficult and complex challenges from local industries, the Valley has never felt so vast! ALL ABOARD! Train Valley 2 is a multiple endings, quick-time events and trains game developed by Alexey Davydov, Sergey Dvoynikov, Timofey Shargorodskiy and Flazm and published by Flazm and META Publishing. Released on April 15th 2019 has received 2,847 reviews of which 2,570 were positive and 277 were negative resulting in a rating of 8.7 out of 10. Currently offered at a significant 92% discount, this title has earned the #9 position in the best deals for games like Big Pharma.10. Rise of Industry
Similarity 72% Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust. Rise of Industry is a management, strategy and economy game developed by Dapper Penguin Studios and published by Kasedo Games. Released on May 02nd 2019 has received 4,089 reviews of which 2,995 were positive and 1,094 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 92% discount, this title has earned the #10 position in the best deals for games like Big Pharma.Free games like Big Pharma on Steam
Check out this fantastic list of free-to-play games like Big Pharma you can enjoy on Steam right now, updated on April 19th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play games like Big Pharma.