Games like Big Pharma on Steam
For those who prefer not to search, lists of the most played, top deals and best free games like Big Pharma are available at the bottom of the page.
Endzone - A World Apart
Endzone is a post-apocalyptic survival city builder, where you start a new civilization with a group of people after an ecological disaster. Build them a new home and ensure their survival in a shattered world, threatened by constant radiation, toxic rain, sandstorms and droughts.Parkasaurus
Parkasaurus is a dinosaur tycoon management simulation where you take care of your dinosaurs by constructing well-designed exhibits, researching specialized technologies, and maximizing profits to expand into the ultimate dinosaur theme park. Do you favor development for guests or your dinosaurs?Train Valley
Build railways, manage traffic and stay accident-free. Play in Europe, America, Japan and USSR in 1830-2020. Complete the story mode from the Gold Rush of 1849 to the first manned spaceflight, and then explore the random mode. Management. Construction. Trains. Welcome to Train Valley!shapez 2
Dive into a factory-building game with the focus on just that – building huge space factories! Construct sprawling multi-level factories and satisfying production lines without limits. Tackle increasingly complex automation challenges at your own pace – you won’t have to worry about enemies.Lords and Villeins
Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy!The Tenants
Become a landlord and deal with problematic tenants as you build your rental property empire. Decide how to react to annoyed neighbors or police interventions. Will you design your apartment for a group of gamer friends or an aspiring musician looking for a new home?Seven Kingdoms 2 HD
Get ready for an exciting real-time strategy game experience like no other with Seven Kingdoms 2! Say goodbye to the monotony of resource gathering and army building, its unique gameplay offers a thrilling blend of city management, trade, industry, espionage, diplomacy, and conquest!Nova Lands
Nova Lands is a factory building, exploration, and island management game. Explore, engage in combat, and automate your industry. The planet you’re on is full of mysteries, creatures, people, and things to do. Welcome to your new home amongst the stars!Restaurant Empire II
Restaurant Empire 2 is the most realistic and comprehensive restaurant business simulation available, featuring 4 cuisines, 600 recipes, 4 huge cities, 2 campaigns with a total of 34 missions, 1400 interior objects, and a mix of business strategy and role-playing gameplay such as cooking contests.Egypt: Old Kingdom
Strategy simulator of the Great Pyramids period, where you take your path from the unification of Egyptian tribes to the foundation of The First Empire. Developed with the assistance of Egyptologists.Stellar Settlers: Space Base Builder
Stellar Settlers is a chill space base/city builder and colony sim game. With unique vertical and horizontal base-building gameplay, settle on 10 hostile alien planets and build your own thriving colony. Get enough materials to build a physics-based Spaceship and try to escape from disasters.Train Fever
It’s the year 1850, and there are great times ahead! Establish a transport company and be its manager. Build infrastructure such as railways and stations, purchase transportation vehicles and manage lines. Fulfill the people’s needs and watch cities evolve dynamically.Mini Settlers
Mini Settlers is a minimalistic city builder! Settle islands, construct cities, and design efficient logistic networks to fulfill your buildings' needs and fuel population growth to adventure into new worlds.Going Medieval
Build and manage your own castle settlement in a land reclaimed by wilderness. With detailed management, survival strategy, and a moddable sandbox world, Going Medieval challenges you to build the mightiest colony this side of the apocalypse.IXION
IXION is an unrelenting, city-building odyssey across the stars. As Administrator of the Tiqqun, DOLOS’ prototype space station, you are tasked with balancing preservation and exploration as you manage infrastructure, resources and crew. Can you keep the flame of humanity alight in the cold dark?King of Retail
The store is your kingdom! Expand your humble boutique into a thriving business: hire the right staff, decorate your displays, and lure in customers. Even your wildest ideas can turn a profit. Why not start a business that sells only white T-shirts and ketchup? PCs and beans? Your rule, your rules!Parkitect
Parkitect is a business simulation game that charges you with the construction and management of theme parks! Bringing back the best of classic theme park games with many new features and content on top. Now supports online co-op with up to 8 players!Moose Miners
Take control of a mining operation run by moose. They mine and sell the gems. You need to decide where to spend the profits. Hire more miners and upgrade their gear. Buy new rails and minecarts to get deeper into the mine. The deeper you get the more valuable gems you will find.Jurassic World Evolution 2
Jurassic World Evolution 2 is the much-anticipated sequel to Frontier’s highly successful Jurassic World Evolution. This bold new era in the Jurassic World Evolution game franchise builds upon the ground-breaking and immersive 2018 management simulation.Cities: Skylines
Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience.Diluvian Winds
Diluvian Winds is a relaxing management game set in a small hamlet at the foot of a lighthouse. Welcome weary travelers and work together to expand your hamlet on land, under the sea, or among the clouds.Most played games like Big Pharma on Steam
Take a look at the top games like Big Pharma that are currently attracting the largest player bases on the Steam platform, as of April 19th 2025.
1. RimWorld
Similarity 54% A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more. RimWorld is a colony sim, base-building and survival game developed and published by Ludeon Studios. Released on October 17th 2018 has received 207,748 reviews of which 203,531 were positive and 4,217 were negative resulting in an impressive rating of 9.7 out of 10. The game has hit the top spot as the #1 most played game like Big Pharma, thanks to its 22,530 peak concurrent players over the last day.2. Factorio
Similarity 66% Factorio is a game about building and creating automated factories to produce items of increasing complexity, within an infinite 2D world. Use your imagination to design your factory, combine simple elements into ingenious structures, and finally protect it from the creatures who don't really like you. Factorio is a automation, base-building and resource management game developed and published by Wube Software LTD.. Released on August 14th 2020 has received 212,622 reviews of which 206,226 were positive and 6,396 were negative resulting in an impressive rating of 9.6 out of 10. While seeing 18,327 players online at once in the last 24 hours, this game is currently ranked #2 among games like Big Pharma based on player count.3. Cookie Clicker
Similarity 60% An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam. Cookie Clicker is a clicker, idler and casual game developed by Orteil and DashNet and published by Playsaurus. Released on September 01st 2021 has received 78,398 reviews of which 75,801 were positive and 2,597 were negative resulting in an impressive rating of 9.5 out of 10. While seeing 12,055 players online at once in the last 24 hours, this game is currently ranked #3 among games like Big Pharma based on player count.4. Revolution Idle
Similarity 51% Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity? Revolution Idle is a casual, simulation and idler game developed by Oni Gaming and Nu Games and published by Oni Gaming. Released on October 11th 2024 has received 3,526 reviews of which 3,002 were positive and 524 were negative resulting in a rating of 8.2 out of 10. With 7,579 concurrent players in the last 24 hours, the game currently holds the #4 spot among the most played games like Big Pharma.5. Cities: Skylines
Similarity 56% Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience. Cities: Skylines is a city builder, simulation and building game developed by Colossal Order Ltd. and published by Paradox Interactive. Released on March 10th 2015 has received 273,857 reviews of which 254,575 were positive and 19,282 were negative resulting in an impressive rating of 9.2 out of 10. With 7,553 concurrent players in the last 24 hours, the game currently holds the #5 spot among the most played games like Big Pharma.6. Supermarket Together
Similarity 52% The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action! Supermarket Together is a simulation, online co-op and multiplayer game developed and published by DeadDevsTellNoLies. Released on August 09th 2024 has received 63,629 reviews of which 60,450 were positive and 3,179 were negative resulting in an impressive rating of 9.3 out of 10. With 6,666 concurrent players in the last 24 hours, the game currently holds the #6 spot among the most played games like Big Pharma.7. Oxygen Not Included
Similarity 57% Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive. Oxygen Not Included is a colony sim, base-building and survival game developed and published by Klei Entertainment. Released on July 30th 2019 has received 127,145 reviews of which 123,019 were positive and 4,126 were negative resulting in an impressive rating of 9.5 out of 10. With 5,652 concurrent players in the last 24 hours, the game currently holds the #7 spot among the most played games like Big Pharma.8. Planet Zoo
Similarity 54% Build a world for wildlife in Planet Zoo. From the developers of Planet Coaster and Zoo Tycoon comes the ultimate zoo sim. Construct detailed habitats, manage your zoo, and meet authentic living animals who think, feel and explore the world you create around them. Planet Zoo is a management, simulation and building game developed and published by Frontier Developments. Released on November 05th 2019 has received 86,491 reviews of which 78,784 were positive and 7,707 were negative resulting in a rating of 9.0 out of 10. With 4,094 concurrent players in the last 24 hours, the game currently holds the #8 spot among the most played games like Big Pharma.9. Supermarket Simulator
Similarity 52% Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand and design your store. Online orders & delivery, shoplifters, security, local market are upcoming. Supermarket Simulator is a simulation, management and economy game developed and published by Nokta Games. Released on February 20th 2024 has received 66,396 reviews of which 62,337 were positive and 4,059 were negative resulting in an impressive rating of 9.2 out of 10. With 4,043 concurrent players in the last 24 hours, the game currently holds the #9 spot among the most played games like Big Pharma.10. Manor Lords
Similarity 54% Manor Lords is a medieval strategy game featuring in-depth city building, large-scale tactical battles, and complex economic and social simulations. Rule your lands as a medieval lord – the seasons pass, the weather changes, and cities rise and fall. Manor Lords is a strategy, city builder and simulation game developed by Slavic Magic and published by Hooded Horse. Released on April 26th 2024 has received 70,570 reviews of which 61,069 were positive and 9,501 were negative resulting in a rating of 8.5 out of 10. With 2,899 concurrent players in the last 24 hours, the game currently holds the #10 spot among the most played games like Big Pharma.Best deals on games like Big Pharma on Steam
Discover fantastic savings with the best discounts on a variety of games like Big Pharma available on Steam right now, updated on April 19th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted games like Big Pharma.
1. Naheulbeuk's Dungeon Master
Similarity 51% A dungeon in danger ! Build, manage, and defend your tower in the satirical heroic fantasy universe of Dungeon of Naheulbeuk. From a shaky establishment to an infamous lair! Naheulbeuk's Dungeon Master is a management, simulation and funny game developed by Artefacts Studio and published by Dear Villagers. Released on November 15th 2023 has received 1,373 reviews of which 988 were positive and 385 were negative resulting in a rating of 7.0 out of 10. Featuring a massive 96% discount, this game currently holds the #1 spot in the best deals for games like Big Pharma.2. Lords and Villeins
Similarity 59% Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy! Lords and Villeins is a colony sim, strategy and city builder game developed by Honestly Games and published by Fulqrum Publishing. Released on November 10th 2022 has received 868 reviews of which 628 were positive and 240 were negative resulting in a rating of 6.9 out of 10. Thanks to its incredible 96% discount, this game is now the #2 best deal in games like Big Pharma.3. Founders' Fortune
Similarity 61% A fantasy village builder focusing on creative building, colonist psychology and base defense. Handle resources, farming, production, tools, diplomacy, families, trading, defense, and research, as well as the wishes, expectations, thoughts, and equipment of every villager. Founders' Fortune is a colony sim, base-building and city builder game developed and published by Dionic Software. Released on December 18th 2020 has received 2,097 reviews of which 1,688 were positive and 409 were negative resulting in a rating of 7.7 out of 10. Thanks to its incredible 95% discount, this game is now the #3 best deal in games like Big Pharma.4. InfraSpace
Similarity 61% Create an extrasolar efficiency utopia from scratch! In this sci-fi city builder you need to start mining operations, plan production, and lay down transportation routes to ensure a smooth supply chain. InfraSpace is a city builder, automation and transportation game developed and published by Dionic Software. Released on September 22nd 2023 has received 1,611 reviews of which 1,297 were positive and 314 were negative resulting in a rating of 7.7 out of 10. Currently offered at a significant 95% discount, this title has earned the #4 position in the best deals for games like Big Pharma.5. Autonauts vs Piratebots
Similarity 52% Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones. Autonauts vs Piratebots is a simulation, strategy and automation game developed by Denki and published by Curve Games. Released on July 28th 2022 has received 480 reviews of which 380 were positive and 100 were negative resulting in a rating of 7.5 out of 10. Currently offered at a significant 95% discount, this title has earned the #5 position in the best deals for games like Big Pharma.6. Snowtopia: Ski Resort Builder
Similarity 60% Build your ideal ski resort. Keep skiers smiling with fresh pistes and fine facilities. Ski, build and chill in the wintry world of Snowtopia where everyone is welcome! Snowtopia: Ski Resort Builder is a simulation, building and management game developed by TeaForTwo and published by Goblinz Publishing and Maple Whispering Limited. Released on December 14th 2022 has received 1,162 reviews of which 713 were positive and 449 were negative resulting in a rating of 6 out of 10. Currently offered at a significant 94% discount, this title has earned the #6 position in the best deals for games like Big Pharma.7. Life is Feudal: Forest Village
Similarity 53% LiF:Forest Village is a city builder with survival aspects in a realistic harsh medieval world. Shape, build and expand your settlement, grow various food to prevent your villagers from avitaminosis and starvation. Possess them for additional micromanagement or simply to wander around. Life is Feudal: Forest Village is a city builder, colony sim and strategy game developed by Mindillusion and published by Bitbox Ltd.. Released on May 26th 2017 has received 5,878 reviews of which 3,895 were positive and 1,983 were negative resulting in a rating of 6.5 out of 10. Currently offered at a significant 93% discount, this title has earned the #7 position in the best deals for games like Big Pharma.8. Train Valley 2
Similarity 54% Build bigger and more complex railway networks than ever before! Building on the success of the original, you’ll get more of what you loved about the original and then some. With increasingly difficult and complex challenges from local industries, the Valley has never felt so vast! ALL ABOARD! Train Valley 2 is a multiple endings, quick-time events and trains game developed by Alexey Davydov, Sergey Dvoynikov, Timofey Shargorodskiy and Flazm and published by Flazm and META Publishing. Released on April 15th 2019 has received 2,847 reviews of which 2,570 were positive and 277 were negative resulting in a rating of 8.7 out of 10. Currently offered at a significant 92% discount, this title has earned the #8 position in the best deals for games like Big Pharma.9. Rise of Industry
Similarity 72% Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust. Rise of Industry is a management, strategy and economy game developed by Dapper Penguin Studios and published by Kasedo Games. Released on May 02nd 2019 has received 4,089 reviews of which 2,995 were positive and 1,094 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 92% discount, this title has earned the #9 position in the best deals for games like Big Pharma.10. Sugar Shack
Similarity 51% Grab some friends, fire up the boiler, and let the syrup flow! Build the world around your cabin as you fulfill orders of hungry villagers with endless sweet tooths. There's never a dull moment in this cozy forest inspired by Quebec lore and art! Sugar Shack is a online co-op, co-op and indie game developed by MadLife Divertissement and published by indie.io. Released on September 14th 2023 has received 303 reviews of which 207 were positive and 96 were negative resulting in a rating of 6.5 out of 10. Currently offered at a significant 92% discount, this title has earned the #10 position in the best deals for games like Big Pharma.Free games like Big Pharma on Steam
Check out this fantastic list of free-to-play games like Big Pharma you can enjoy on Steam right now, updated on April 19th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play games like Big Pharma.